One Day in My Body

Piyah must walk on her hands because she was born with a body that ends at her waist. Joe is the first survivor of a successful hands and face transplant. Tumors have left Reggie's face unrecognizable, and threaten his independence.

Twenty-seven-year-old Taffy presents physically as a 4-year-old; Adrienne's rare disorder has left both her eyes completely covered by skin; Baby Brody undergoes a procedure to fix a severe cleft palate.

Zahra is housebound by a rare condition, but new prosthetics may be her ticket to freedom; Mahogany's leg weighs nearly 100 pounds due to lymphedema. Joseph was born without a jaw but won't let it stop him.

There are only two foods that won't send Caroline into anaphylaxis; touching almost anything causes Ariana's butterfly skin to blister and tear; Aleazia's cystic hygroma caused his jaw and tongue to swell, permanently freezing his mouth open.

See how an allergic reaction left Kirtus with vitiligo, alopecia and bone loss; a surgery could change his life; Portia's rare skin condition may exist in fewer than 25 people worldwide; Dani lost all four limbs and now she fights to walk unassisted.

Tiffany has progeria, a condition that causes her to age rapidly, yet she's already outlived her life expectancy; single dad Ryan was born with arthrogryposis, leaving his arms and legs fused.

Zahra is housebound by a rare condition, but new prosthetics may be her ticket to freedom; Mahogany's leg weighs nearly 100 pounds due to lymphedema. Joseph was born without a jaw but won't let it stop him.

Twenty-seven-year-old Taffy presents physically as a 4-year-old; Adrienne's rare disorder has left both her eyes completely covered by skin; Baby Brody undergoes a procedure to fix a severe cleft palate.

Piyah must walk on her hands because she was born with a body that ends at her waist. Joe is the first survivor of a successful hands and face transplant. Tumors have left Reggie's face unrecognizable, and threaten his independence.

See how an allergic reaction left Kirtus with vitiligo, alopecia and bone loss; a surgery could change his life; a look at Portia's rare skin condition that may exist in fewer than 25 people worldwide; Dani lost all four limbs and now she fights to walk unassisted.

Tiffany has progeria, a condition that causes her to age rapidly, yet she's already outlived her life expectancy; single dad Ryan was born with arthrogryposis, leaving his arms and legs fused.

There are only two foods that won't send Caroline into anaphylaxis; touching almost anything causes Ariana's butterfly skin to blister and tear; Aleazia's cystic hygroma caused his jaw and tongue to swell, permanently freezing his mouth open.